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Inside U365 - Publication

Writer's pictureGallia Straley

The Power of Breath: Insights from Dr. Jack Feldman


In this comprehensive exploration of the science of breathing, we delve into the intricate relationship between respiration, mental health, and physical performance with Dr. Jack Feldman, a leading expert in neurobiology.


Introducing Dr. Jack Feldman

Dr. Jack Feldman is a distinguished Professor of Neurobiology at the University of California, Los Angeles, renowned for his groundbreaking research in the neuroscience of breathing.


His work has significantly advanced our understanding of the neural mechanisms that control respiration, which is essential for life. Feldman's pioneering studies have identified key brain regions responsible for generating the rhythmic patterns of breathing, fundamentally linking breathing to various physiological and psychological processes.

Dr. Jack Feldman speaking

Photo by Balint Miko on Unsplash

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Why We Breathe

Breathing is an involuntary process that sustains life by delivering oxygen to our cells and removing carbon dioxide, a waste product of metabolism. However, it serves more than just a physiological function. Breathing patterns can influence our mental state, stress levels, and overall well-being. Understanding why we breathe and how we can optimize this process can lead to significant improvements in health and cognitive function.


Neural Control of Breathing: 'Pre-Botzinger Complex'

The pre-Botzinger complex is a cluster of neurons located in the brainstem that plays a critical role in generating the rhythmic pattern of breathing. Discovered by Dr. Feldman and his colleagues, this area is responsible for initiating each breath. The neurons in this region activate in a rhythmic manner, sending signals to respiratory muscles, primarily the diaphragm, to facilitate inhalation. Understanding this neural control is essential for grasping how breathing is regulated and can be manipulated for health benefits.


Nose vs Mouth Breathing

Breathing through the nose and mouth serves different purposes and has varying effects on the body. Nasal breathing is generally preferred as it helps filter, warm, and humidify the air before it reaches the lungs. It also promotes optimal oxygen exchange and can enhance relaxation. Mouth breathing, on the other hand, is often utilized during intense physical activity when the body requires a larger volume of air. Understanding these differences can help individuals choose the appropriate breathing method for different situations.

Nasal breathing illustration

Skeletal vs. Smooth Muscles: Diaphragm, Intracostals & Airway Muscles

The muscles involved in breathing can be categorized into skeletal and smooth muscles. The diaphragm and intercostal muscles are skeletal muscles that require neural input for contraction.


These muscles are crucial for inhalation and exhalation during normal breathing. In contrast, the smooth muscles located in the airways control the diameter of these passages and can influence airflow. Conditions like asthma highlight the importance of these smooth muscles, as their inappropriate contraction can lead to difficulty in breathing.

Skeletal muscles diagram

Photo by Nigel Msipa on Unsplash


Two Breathing Oscillators: Pre-Botzinger Complex & Parafacial Nucleus

In addition to the pre-Botzinger complex, research has identified another significant brain region known as the parafacial nucleus, which contributes to the regulation of breathing patterns.


While the pre-Botzinger complex primarily drives rhythmic inhalation, the parafacial nucleus is involved in generating active expiration. Together, these two oscillators ensure a balanced and efficient respiratory cycle, highlighting the complexity of the neural control of breathing.

Brainstem respiration control

How We Breathe Is Special (Compared to Non-Mammals)

Mammals possess a unique respiratory system characterized by the presence of a diaphragm, which enables efficient inhalation and exhalation. Unlike reptiles and amphibians, which rely on different breathing mechanisms, mammals can actively control inhalation while allowing exhalation to occur passively.


This evolutionary advantage allows for a greater surface area in the lungs, facilitating improved oxygen uptake and supporting the high metabolic demands of mammalian brains.

Mammal respiratory system

Stomach & Chest Movements During Breathing

Breathing involves the coordinated movement of both the chest and abdomen. During inhalation, the diaphragm contracts and moves downward, expanding the thoracic cavity and drawing air into the lungs.


Simultaneously, the rib cage rises as the intercostal muscles contract. This coordinated action causes the abdomen to expand outward, as the diaphragm pushes down on the abdominal organs. Understanding these movements is crucial for optimizing breathing techniques for relaxation, exercise, and overall health.

Breathing movements illustration

Physiological Sighs, Alveoli Re-Filling, Bombesin

Physiological sighs are deep breaths that occur naturally and serve a vital purpose in maintaining lung health. These sighs help to re-inflate alveoli, which can collapse during normal breathing. The act of sighing increases lung volume and facilitates gas exchange, ensuring efficient oxygen delivery. Research has shown that specific neuropeptides, such as Bombesin, can influence the frequency of sighing, revealing a fascinating link between neurobiology and respiratory health.

Physiological sigh illustration

If We Don’t Sigh, Our Lung (& General) Health Suffers

Failure to sigh regularly can lead to poor lung function and overall health deterioration. The lungs rely on these deep breaths to maintain optimal surface area for gas exchange. In conditions where sighing is suppressed, such as in certain neurological disorders, individuals may experience significant respiratory challenges. Encouraging regular sighing can be a simple yet effective strategy for promoting lung health and preventing complications.

Healthy lungs diagram

Photo by Brooke Lark on Unsplash


Breathing, Brain States & Emotions

The relationship between breathing patterns and emotional states is profound. Different emotional states, such as stress or relaxation, can alter breathing rates and patterns. Conversely, consciously changing one's breathing can influence emotional states.


For example, slow, deep breathing can promote relaxation and reduce stress, while rapid, shallow breathing may exacerbate anxiety. Understanding this interplay can empower individuals to use breath as a tool for emotional regulation.

Emotional breathing exercise

Photo by bruce mars on Unsplash


Meditating Mice, Eliminating Fear

Recent research has explored the effects of breath control and meditation-like practices in rodents, demonstrating that these techniques can significantly alter emotional responses. Mice trained to breathe slowly exhibited reduced fear responses in stressful situations. This finding suggests that the benefits of breathwork and meditation extend beyond humans, opening new avenues for understanding the mechanisms behind emotional regulation through breathing.

Mice meditation study

Brain States, Amygdala, Locked-In Syndrome, Laughing

The amygdala plays a crucial role in processing emotions and can influence breathing patterns. In individuals with locked-in syndrome, where volitional control of breathing is lost, emotional responses can still affect breathing rates. Notably, laughter can trigger distinct breathing patterns, showcasing the connection between emotion and respiration. Understanding these relationships enhances our knowledge of how breathing can be used therapeutically to manage emotional and psychological states.


Facial Expressions

Facial expressions are a powerful form of non-verbal communication. They can reveal a person's emotional state even before they speak. This innate ability to read faces is crucial in social interactions, helping to establish connections and empathy.

Facial expressions in communication

Emotional Control vs. Volitional Control

Humans possess both emotional and volitional control over facial muscles. Emotional responses often manifest involuntarily, while volitional control allows us to manipulate our expressions intentionally. Understanding this distinction can enhance our ability to communicate effectively.

Volitional control of facial expressions

Locus Coeruleus & Alertness

The locus coeruleus is a small nucleus in the brainstem that plays a vital role in arousal and alertness. It releases norepinephrine, which influences various brain functions, including attention, memory, and stress responses.


This area is interconnected with breathing patterns, suggesting a link between respiration and cognitive states.


Breathing and Alertness

Research indicates that inhalation can heighten alertness and improve memory encoding. This connection highlights the importance of breathing techniques in enhancing cognitive performance. By consciously altering our breathing, we can potentially influence our mental state.

Breathing and cognitive alertness

Photo by Erwan Hesry on Unsplash


Breath Holds, Apnea, Episodic Hypoxia, Hypercapnia

Breath holds can significantly impact brain function. During breath holds, the body experiences changes in oxygen and carbon dioxide levels, leading to various physiological responses. Understanding the effects of breath holds, including episodic hypoxia and hypercapnia, is essential for optimizing breathwork practices.

Breath hold exercise

Photo by John Arano on Unsplash


Episodic Hypoxia

Episodic hypoxia involves alternating periods of low oxygen and normal air. This practice can enhance cognitive function and motor performance, as observed in studies with both animals and humans. The controlled reduction of oxygen can stimulate neuroplasticity and improve overall brain health.

Episodic hypoxia illustration

Stroke, Muscle Strength, TBI

Traumatic brain injury (TBI) and strokes can severely impact physical and cognitive functions. Rehabilitation techniques that incorporate breathwork are showing promise in improving muscle strength and recovery outcomes. Understanding the relationship between breathing and these conditions can inform therapeutic approaches.

Stroke rehabilitation exercise

Photo by Jenny Hill on Unsplash


Breathwork in Rehabilitation

Integrating breathwork into rehabilitation programs can enhance recovery from TBI and strokes. Techniques that focus on controlled breathing may aid in muscle activation and cognitive recovery, offering a holistic approach to treatment.


Cyclic Hyperventilation

Cyclic hyperventilation involves controlled patterns of rapid breathing followed by breath holds. This technique can stimulate various physiological responses, including increased alertness and improved mood. Understanding how to effectively implement cyclic hyperventilation can enhance its benefits.

Photo by Lidya Nada on Unsplash


Applications of Cyclic Hyperventilation

Practitioners of cyclic hyperventilation often report heightened energy levels and improved focus. This technique can be particularly beneficial for those needing an energy boost or cognitive clarity during demanding tasks.


Hyperbaric Chambers

Hyperbaric chambers provide a controlled environment for breathing oxygen at higher than normal atmospheric pressures. This method can enhance oxygen delivery to tissues, potentially aiding recovery from various medical conditions. Exploring the implications of hyperbaric therapy can open new avenues for health optimization.


Benefits of Hyperbaric Therapy

Research suggests that hyperbaric oxygen therapy may improve healing in injuries and enhance cognitive function. Understanding the mechanisms by which this therapy operates can help incorporate it into broader health strategies.

Photo by Toa Heftiba on Unsplash


Nasal Breathing, Memory, Right vs. Left Nostril

Nasal breathing has been linked to improved memory and cognitive function. Studies indicate that breathing through the nose may activate specific brain pathways associated with memory encoding and recall.

Photo by Mockup Free on Unsplash


Right vs. Left Nostril Breathing

Some theories suggest that breathing through different nostrils may influence brain activity, with right nostril breathing potentially enhancing alertness and left nostril breathing promoting calmness. While more research is needed, these insights can inform breathwork practices.


Breathing Coordinates Everything: Reaction Time, Fear, etc.

Breathing patterns can significantly influence various physiological responses, including reaction time and fear responses. By understanding how breath affects these functions, individuals can learn to harness breathwork for improved performance in high-stress situations.


Breathing Techniques for Performance

Incorporating specific breathing techniques can enhance reaction times and reduce fear responses. Athletes and performers can benefit from training these techniques to optimize their performance under pressure.

Photo by Ale Romo on Unsplash


Dr. Feldman’s Breathwork Protocols, Post-Lunch

Dr. Feldman emphasizes the importance of breathwork, particularly after lunch, to combat post-lunch fatigue. Simple breathwork exercises can rejuvenate energy levels and enhance focus, making them a valuable tool for maintaining productivity throughout the day.

Photo by bruce mars on Unsplash


Implementing Breathwork After Lunch

Practicing short, focused breathwork sessions after lunch can counteract the natural dip in energy. Techniques like box breathing or cyclic hyperventilation can effectively restore alertness and improve cognitive function.

Breathwork for energy boost

Deliberately Variable Breathwork: The Feldman Protocol

The Feldman protocol encourages variability in breathwork practices to enhance their effects. By alternating between different patterns and techniques, individuals can explore the unique benefits of each approach and discover what works best for them.


Benefits of Variability in Breathwork

Varying breathwork techniques can prevent monotony and enhance engagement. This approach allows practitioners to fine-tune their practices to their needs, maximizing the benefits of breathwork.


Magnesium Threonate & Cognition & Memory

Magnesium threonate has gained attention for its potential cognitive benefits, particularly in enhancing memory and learning. Research suggests that this form of magnesium can improve synaptic plasticity, making it a valuable supplement for cognitive health.

Magnesium threonate benefits

Exploring Cognitive Enhancements

Taking magnesium threonate may lead to improved cognitive function and memory retention. Individuals looking to enhance their cognitive abilities may consider incorporating this supplement into their routine.


Gratitude for Dr. Feldman’s Highly Impactful Work

Dr. Feldman's contributions to the understanding of breathing and its effects on cognition and emotional health are invaluable. His research has paved the way for practical applications of breathwork in various fields, including rehabilitation and performance enhancement.

 

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